Formulasi dan Karakterisasi Buccal Film Salbutamol Sulfat
نویسندگان
چکیده
منابع مشابه
Effect of permeation enhancers in the mucoadhesive buccal patches of salbutamol sulphate for unidirectional buccal drug delivery
The purpose of this work was to study the effect of various permeation enhancers on the permeation of salbutamol sulphate (SS) buccal patches through buccal mucosa in order to improve the bioavailability by avoiding the first pass metabolism in the liver and possibly in the gut wall and also achieve a better therapeutic effect. The influence of various permeation enhancers, such as dimethyl sul...
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OBJECTIVE The objectives of the study were to determine the absolute bioavailability of fentanyl from fentanyl buccal soluble film, estimate the percentage of a fentanyl dose absorbed through the buccal mucosa, and compare the bioavailability of equivalent doses administered either as single or multiple dose units. DESIGN Open-label, randomized, four-period, Latin-square crossover pharmacokin...
متن کاملeffect of permeation enhancers in the mucoadhesive buccal patches of salbutamol sulphate for unidirectional buccal drug delivery
the purpose of this work was to study the effect of various permeation enhancers on the permeation of salbutamol sulphate (ss) buccal patches through buccal mucosa in order to improve the bioavailability by avoiding the first pass metabolism in the liver and possibly in the gut wall and also achieve a better therapeutic effect. the influence of various permeation enhancers, such as dimethyl sul...
متن کاملDesign and In-vitro Evaluation of Muco- Adhesive Buccal Tablets of Salbutamol Sulphate
In the present investigation an attempt has been made to design efficacious and prolonged release mucoadhesive tablet of salbutamol sulphate using various polymers to avoid the first pass metabolism to reduce dossing frequency and to improve patient compliance. Mucoadhesive buccal tablet of salbutamol sulphate were fabricated with objective of avoiding first pass metabolism and to improve its b...
متن کاملDevelopment and characterization of mucoadhesive patches of salbutamol sulfate for unidirectional buccal drug delivery.
Buccal patches of salbutamol sulfate were prepared using five different water soluble polymers in various proportions and combinations using PEG-400/PG as plasticizers. A 32 full factorial design was used to design the experiments for each polymer combination. Patches were laminated on one side with a water impermeable backing layer for unidirectional drug release. The thickness of medicated pa...
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ژورنال
عنوان ژورنال: Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan
سال: 2018
ISSN: 2715-4181
DOI: 10.33772/pharmauho.v4i1.4640